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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
NEK1
All Species:
15.45
Human Site:
S733
Identified Species:
28.33
UniProt:
Q96PY6
Number Species:
12
Phosphosite Substitution
Charge Score:
0
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q96PY6
NP_036356.1
1258
142828
S733
E
K
G
K
Q
N
L
S
D
T
F
E
I
N
V
Chimpanzee
Pan troglodytes
XP_001153129
1258
142786
S733
E
K
G
K
Q
N
L
S
D
T
C
E
I
N
V
Rhesus Macaque
Macaca mulatta
XP_001082793
1258
142958
S733
E
K
G
K
Q
H
L
S
D
T
C
E
I
N
V
Dog
Lupus familis
XP_543184
1286
146207
S761
E
E
E
K
Q
C
H
S
D
T
C
E
I
V
V
Cat
Felis silvestris
Mouse
Mus musculus
P51954
1203
136672
S685
E
K
E
K
Q
H
H
S
G
S
C
E
T
V
G
Rat
Rattus norvegicus
NP_001099552
648
74414
V152
G
D
F
G
I
A
R
V
L
N
S
T
V
E
L
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001513277
864
98961
D368
D
H
Y
H
A
Q
L
D
I
L
Q
K
R
P
D
Chicken
Gallus gallus
XP_420401
1281
145243
K747
E
K
G
R
K
D
D
K
N
I
S
E
S
D
G
Frog
Xenopus laevis
Q7ZZC8
944
104521
S448
G
V
N
Q
S
A
G
S
E
V
L
E
P
L
L
Zebra Danio
Brachydanio rerio
Q90XC2
697
76523
R201
Y
E
L
A
S
L
K
R
A
F
E
A
A
N
L
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
XP_782796
1091
120115
E595
A
K
L
K
E
Q
L
E
K
Q
R
R
D
A
Y
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Q9CAU7
606
68016
L110
E
E
K
L
C
K
W
L
V
Q
I
L
L
A
L
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
P48479
858
94329
I362
D
R
L
V
A
Q
E
I
E
S
L
Q
Q
K
F
Conservation
Percent
Protein Identity:
100
99.6
97.5
85
N.A.
79.2
45.9
N.A.
30.2
66.2
22.4
22.7
N.A.
N.A.
N.A.
N.A.
32.9
Protein Similarity:
100
99.7
98.4
90.8
N.A.
85.6
48.5
N.A.
44.3
78
39.2
34.4
N.A.
N.A.
N.A.
N.A.
48.5
P-Site Identity:
100
93.3
86.6
60
N.A.
40
0
N.A.
6.6
26.6
13.3
6.6
N.A.
N.A.
N.A.
N.A.
20
P-Site Similarity:
100
93.3
93.3
66.6
N.A.
53.3
13.3
N.A.
20
60
33.3
20
N.A.
N.A.
N.A.
N.A.
26.6
Percent
Protein Identity:
N.A.
N.A.
N.A.
21.9
N.A.
20.1
Protein Similarity:
N.A.
N.A.
N.A.
33.7
N.A.
35.1
P-Site Identity:
N.A.
N.A.
N.A.
6.6
N.A.
0
P-Site Similarity:
N.A.
N.A.
N.A.
26.6
N.A.
33.3
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
8
0
0
8
16
16
0
0
8
0
0
8
8
16
0
% A
% Cys:
0
0
0
0
8
8
0
0
0
0
31
0
0
0
0
% C
% Asp:
16
8
0
0
0
8
8
8
31
0
0
0
8
8
8
% D
% Glu:
54
24
16
0
8
0
8
8
16
0
8
54
0
8
0
% E
% Phe:
0
0
8
0
0
0
0
0
0
8
8
0
0
0
8
% F
% Gly:
16
0
31
8
0
0
8
0
8
0
0
0
0
0
16
% G
% His:
0
8
0
8
0
16
16
0
0
0
0
0
0
0
0
% H
% Ile:
0
0
0
0
8
0
0
8
8
8
8
0
31
0
0
% I
% Lys:
0
47
8
47
8
8
8
8
8
0
0
8
0
8
0
% K
% Leu:
0
0
24
8
0
8
39
8
8
8
16
8
8
8
31
% L
% Met:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% M
% Asn:
0
0
8
0
0
16
0
0
8
8
0
0
0
31
0
% N
% Pro:
0
0
0
0
0
0
0
0
0
0
0
0
8
8
0
% P
% Gln:
0
0
0
8
39
24
0
0
0
16
8
8
8
0
0
% Q
% Arg:
0
8
0
8
0
0
8
8
0
0
8
8
8
0
0
% R
% Ser:
0
0
0
0
16
0
0
47
0
16
16
0
8
0
0
% S
% Thr:
0
0
0
0
0
0
0
0
0
31
0
8
8
0
0
% T
% Val:
0
8
0
8
0
0
0
8
8
8
0
0
8
16
31
% V
% Trp:
0
0
0
0
0
0
8
0
0
0
0
0
0
0
0
% W
% Tyr:
8
0
8
0
0
0
0
0
0
0
0
0
0
0
8
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _